BRAIN-EATING AMOEBA


Aaditya Deore

BRAIN-EATING AMOEBA


Why in news :

  • A DEADLY BRAIN-EATING amoeba has killed a nine-year-old child and infected two others in Kerala’s Kozhikode
  • The first case in India was reported in 1971.
  • The first case in Kerala in 2016.
  • There have been fewer than 500 cases of PAM (Primary amoebic meningoencephalitis) worldwide since 1965, though it has been reported in every continent except Antarctica.

Pathogen :

  • Name : Naegleria fowleri.
  • It is a single-celled organism that lives in warm, fresh water and soils around the world and thrives in high temperatures up to 46°C.
  • The amoeba is found in lakes and rivers, swimming pools, splash pads, surf parks, or other recreational venues that are poorly maintained or minimally chlorinated.
  • Naegleria fowleri enters the body through the nose, usually when people are swimming.
  • It travels to the brain, where it destroys brain tissue and causes swelling.
  • Naegleria fowleri infection cannot come from drinking water contaminated with the amoeba.

Infection :

  • Name : Primary amoebic meningoencephalitis (PAM).
  • PAM is non-communicable.

Symptoms :

  • In the initial stage include headache, fever, nausea, and vomiting.
  • The patient may later experience a stiff neck, confusion, seizures, hallucinations  and may slip into a coma.
  • According to the US Centres for Disease Control and Prevention (CDC), most patients die within 1 to 18 days after symptoms begin.
  • Globally reported fatality rate is 97%

Treatment :

  • Scientists have not identified an effective treatment for the disease yet.
  • PAM is usually treated with a combination of drugs including amphotericin B, fluconazole, azithromycin, rifampicin, miltefosine and dexamethasone.

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